Interesting Case of the Month - (IGHP, ICOM) - June
june 2025
Clinical History-
33-year-old male was admitted with complaints of abdominal pain underwent segmental jejunal resection for suspected jejunal Intussusception.
Radiology-
NCCT Scan of abdomen-
There is evidence of abrupt narrowing present at mid segment of jejunum with distal Bird Beak appearance. Proximal small bowel is moderately dilated.
Gross Images-
Microscopic Images-
Microscopic image showed dense diffuse infiltrate of intermediate sized cell with areas of starry sky appearance.
Immunohistochemistry -
Immunohistochemistry performed for CD45, CD20, CD3, BCL2, BCL6, CD10, KI67 and EBV. The neoplastic cells are positive for CD20, CD10 and BCL6. The cells are negative for CD3, BCL2 and EBV. Ki67 index was approaching 100%.
Diagnosis-
MALToma
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Burkitts Lymophoma
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Burkitt’s lymphoma is among the rare causes of intussusception and it is an aggressive, malignant non-Hodgkin’s lymphoma with rapid growth of B cells. Burkitt’s lymphoma affects mainly the terminal part of the ileum, the cecum and the appendix. This is due to the high concentration of lymphoid tissue in the ileo-cecal junction. Burkitt’s tumor, like all lymphomas, extends into the submucosal and mucosal layer circumferentially, and manifests as a parietal digestive thickening or as a mural mass. The mural mass may sometimes invaginate into the downstream digestive segment causing intusuception.
Diffuse Large B Cell Lymphoma
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Metastatic Carcinoma
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