Interesting Case of the Month - (IGHP, ICOM) - August
august 2025
Clinical History-
67-year-old malewithabdominal pain and features of acute enteritis. AFP- normal, Serology- for viral markers negative.
From the images below identify the likely disease?
Radiology-
USG-
Liver showed a solitary mass measuring 3.0 x 2.8 cm. Adjacent liver tissue showed heterogenous liver parenchyma.
Microscopic Images-
Microscopic examination showed a population of atypical cells with clear cytoplasm.
Immunohistochemistry-
Immunohistochemistry performed showed the clear cells are diffusely positive for Arginase and Glypican 3
Diagnosis-
Steatohepatitic Hepatocellular Carcinoma
Adrenal Cell Carcinoma
Cholangiocarcinoma
Clear Cell Hepatocellular Carcinoma
