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Interesting Case of the Month - (IGHP, ICOM) - July

ugie

Clinical History-

8-year-old boy known HBsAg positive, presented with hematemesis. UGIE showed features of esophageal varices. LFT Bilirubin 0.8mg/dl, SGOT/ SGPT-70/60 U/l, SAP/ GGT -75/ 40 U/L, Serum Albumin-3.5 mg/ dl. USG abdomen showed coarse liver echotexture? CLD. Liver biopsy was performed for evaluation. From the images below identify the likely disease?

Upper GI Endoscopy Image-

Microscopic Images-

Special Stains-

MT stain showed presence of broad fibrous septae. Orcein stain highlighted HBsAg positive antigen with hepatocytes.

A. Liver Cirrhosis with HBsAg-
B. Chronic Hepatitis with HBsAg-
C. Congenital Hepatic Fibrosis with Cirrhosis
D. Congenital Hepatic Fibrosis with HBsAg-