Interesting Case of the Month - (IGHP, ICOM) - May
may 2025
Clinical History-
46-year-old obese female with height of 166cm and weight of 112 Kg and H/o NASH related CLD with features of decompensation including ascites, jaundice and HE underwent LDLT LFT Bili -3.0 mg/dl, SGOT/ SGPT-35/ 31, SAP/ GGT-92/ 19 and Protein/ Alb-6.2/ 2.4. ANA was positive (1:20)
Radiology-
HRCT -Showed features of chronic liver disease with splenomegaly and portosystemic collaterals.
Gross Image-
Expand liver cut surface showed regular margins and variegated greenish yellow cut surface.
Microscopic Examination -
Microscopic examination showed moderate to severe steatosis with cholangiolar cholestasis and areas of bridging necrosis
Special Stain Performed -
Masson’ trichrome stain showed pericellular and periportal fibrosis with bridging. alongside areas of multi acinar and bridging necrosis.
Immunohistochemistry -
IHC performed for CK8/ 18highlighted multiple Mallory Denk Bodies–
