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Interesting Case of the Month - (IGHP, ICOM) - January

january 2025

Clinical History-

29-year-old male with abdominal pain andmalena single episode. Underwent EUS guided biopsy from the head mass.

From the images below identify the likely disease.

On endoscopy-

UGIE- Large umblicated and ulcerated lesion in Duodenum.

Microscopic Images-

Histology images showed bits of ulcerated small bowel mucosa with presence of proliferated spindle cells in ulcer bed.

Immunohistochemistry Performed-

Immunohistochemistry performed showed the atypical spindle cells are positive for CD34, CD117 and DOG1. Ki67 index is 5-6%.

Diagnosis-

Granulomatous Duodenitis
Gastrointestinal Stromal Tumor
Benign Ulcer
Leiomyoma