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Interesting Case of the Month - (IGHP, ICOM) - September

september 2024

Clinical History-

17-year-old maleunderwent UGIE for abdominal pain.

From the images below identify the likely disease?

On endoscopy-

UGIE- showed multiple gastric and duodenal polyps? Adenomatous

Microscopic Images-

Histology showingdiffuse infiltrate of lymphoplasmacytic cells

Immunohistochemistry-

IHC performed for CD3, CD20, Ki67, CD10, BCL2, CD5, CD23, Cyclin D1.The atypical cells are diffusely positive for CD20 and CD10 approaching 100%, The atypical cells are negative for other immunostains.

Diagnosis-

Lymphoid polyp
Inflammatory polyp
Lymphoproliferative lesion
Adenomatous Polyp