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Interesting Case of the Month - (IGHP, ICOM) - October

october 2026

Clinical History-

67-year-old male complaint of pain abdomen for 2-3 weeks. From the images below identify the likely disease?

Microscopic Images

Microscopic examination of the Ileal biopsy showed features of a lymphoproliferative disorder.

Immunostains performed-

IHC performed showed neoplastic cells are diffusely positive for CD20, PAX5, BCL6 and BCL2 and are negative for CDX2. KI67 labelling index is upto 75-80%.

BCL2

KI67

CD20

BCL

PAX

Diagnosis-

Nodular Lymphoid Hyperplasia
Chronic active Ileitis
Low-Grade Follicular Lymphoma (LGFL)
Enteric Fever