Interesting Case of the Month - (IGHP, ICOM) - August
august 2026
Clinical History-
57-year-old female complaint of pain abdomen for 7-8 months, weight loss. From the images below identify the likely disease?
Radiology-
CECT-Diffusely bulky pancreas with peripancreatic halo ? AIP
Microscopic Images
Microscopic examination of the pancreatic biopsy showed benign pancreatic acini alongside large areas of fibrosis. The fibrosis has vague storiform arrangement of spindle cells . Mild periductal inflammatory infiltrate comprising oflymphoplasmacytic cells.
Special Stains Performed-
MT stain showed areas of fibrosis
Immunostains performed-
IHC performed for IgG4 showed 15-18 IgG4 positive cells / hpf
Diagnosis-
Adenocarcinoma Pancreas
Chronic pancreatitis
Metastatic carcinoma
Autoimmune Pancreatitis (AIP)
