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Interesting Case of the Month - (IGHP, ICOM) - September

september 2025

Clinical History-

35-year-old malewithabdominal pain, associated with fever with chills off and on and nausea and vomiting. AFP- normal, Serology- for viral markers negative. CBC showed eosinophilia.

From the images below identify the likely disease?

Radiology-

USG-
Liver showed multiple small lesions largest measuring 3.0 x 2.8 cm.

Microscopic Images-

Microscopic examination showed eosinophilic abscess with multiple cholesterol clefts.

Special Stain Performed--

PAS, MT and Orcein stains performed showed presence of CharcotLayden crystals.

Diagnosis-

Eosinophilic granuloma
Granulomatous Hepatitis
Cholangiocarcinoma
Schistosomiasis