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Interesting Case of the Month - (IGHP, ICOM) - February

february 2026

Clinical History-

68-year-old malewith h/o pain abdomen with off and on pain

From the images below identify the likely disease?

Radiology-

CECT Abdomen-

Mass in head of pancreas measuring 4.5 x 4.0 x 3.5 cm

Microscopic Images-

Microscopic examination showed from the cytology smears revealed cellular smears, showing loose clusters and isolated malignant cells characterized by nuclear enlargement, pleomorphism, and hyperchromasia. A few multinucleated giant cells and occasionalbizzarre cells noted. Scanty large atypical cells with features of cellular(polymorphs) cannibalism noted.

Histology-

Section from the pancreatic biopsy showed scanty large atypical cell in fibro collagenous stroma

Diagnosis-

Anaplastic Carcinoma
Chronic Pancreatitis
Solid Pseudopapillary Carcinoma
Neuroendocrine Tumor