Interesting Case of the Month - (IGHP, ICOM) - January
january 2026
Clinical History-
43-year-old malepost living donor liver transplant POD 3.5 months post-transplant. Presented with new onset ascites and progressively worsening LFT’s. LFT Total Bili- 18.7 mg/ dl, SGOT-726 U/ L, SGPT- 281 U/L, SAP-781 U/L. Albumin- 2.8 mg/ dl. INR 1.18. Renal parameters and electrolytes are stable. Doppler USG Hepatic artery RI-1.0 with normal venous inflow and outflow.
From the images below identify the likely disease?
Microscopic Images-
Microscopic examination showed an areas of perivenular hepatocyte loss with prominent central perivenulitis.
Special Stains Performed-
MT and Rhodanine stains performed no increase in fibrosis or copper stores.
Diagnosis-
Biliary Cholangiopathy
HVOTO
Hepatic artery thrombosis
Late Acute Rejection
