Interesting Case of the Month - (IGHP, ICOM) - September
september 2026
Clinical History-
54-year-old male underwent liver transplant for sclerosis cholangitis. Sections from liver explant.
Microscopic Images
Microscopic examination from the explant tissue showed dilated ducts filled with incipissated bile with areas of periductal fibrosis. Several dilated ducts showed multiple entangled bacterial colonies.
Special Stains Performed-
MT stain showed areas of bridging fibrosis with nodule formation
Immunostains performed-
IHC performed for CK7 showed areas of bile ductular proliferation
Diagnosis-
Cholangiocarcinoma
Alcoholic cirrhosis
Metastatic carcinoma
Sclerosis cholangitis with bacterial colonisation of bile ducts
